for the most part, with the game still being new, it will more than likely be preference at this point. There is no one true perfect set up in my opinion (in all honesty it would be boring that way)
However, something I highly highly recommend is finding out what abilities wont work with certain things.
examples :
- run speed up =/= rolling speed up
- bomb range up =/= sprinkler throw range up
it's kinda silly that they don't give you some benefit or at the very least tell you, but it is what it is