In the high ranked lobbies the weapons that I have seen destroy are mainly the tentatek , eliter or splatters cope, a team of blasters can be annoying also but that is probably because of lag. Ima list them out
E-Liter 3k, either one
Tentatek splattershot
Splatterscope
Blasters, preferably one with bubbler.
Gold dynamo or krakon splat roller
Ima go In to detail about annoying combinations of weapons that I have faced.